Find out the most recent publications from the Lipidomics research group.



1. Fatty acids profiling of goose barnacle (Pollicipes pollicipes) tissues to evaluate nutritional quality and confirm harvesting location

Mamede, R., Santos, A., Sousa, A., Díaz, S., Marques, S.C., Leandro, S.M., Domingues, M.R., Calado, R., Ricardo, F., Journal of Food Composition and Analysis, 2024, 127.

2. Short-communication: Study of fatty acid metabolites in microbial conjugated fatty acids-enrichment of milk and discovery of additional undescribed conjugated linolenic acid isomers

Fontes, A.L., Neves, B., Conde, T., Couto, D., Pimentel, L.L., Rodríguez-Alcalá, L.M., Domingues, M.R., Gomes, A.M., Food Chemistry, 2024, 432.

3. Microbial Conjugated Linolenic Acid-Enriched Fermented Milk Using Lipase-Hydrolyzed Flaxseed Oil: Biochemical, Organoleptic and Storage Traits

Fontes, A.L., Pimentel, L.L., Monteiro, M.J.P., Domingues, M.R., Rodríguez-Alcalá, L.M., Gomes, A.M., Foods, 2024, 13.

4. Lipidomic fingerprinting of the red seaweed Asparagopsis spp. evidencing specific profiling in gametophyte and tetrasporophyte life stages

Lopes, D., Rey, F., Melo, T., Pinho, M., Moreira, A.S.P., Pes, K., Mata, L., Domingues, M.R., Algal Research, 2024, 77.

5. Mapping the lipidome in mitochondria-associated membranes (MAMs) in an in vitro model of Alzheimer’s disease

Fernandes, T., Melo, T., Conde, T., Neves, B., Domingues, P., Resende, R., Pereira, C.F., Moreira, P.I., Domingues, M.R., Journal of Neurochemistry, 2024.

6. Plasma lipidomics analysis reveals altered profile of triglycerides and phospholipids in children with Medium-Chain Acyl-CoA dehydrogenase deficiency

Guerra, I.M.S., Ferreira, H.B., Maurício, T., Pinho, M., Diogo, L., Moreira, S., Goracci, L., Bonciarelli, S., Melo, T., Domingues, P., Domingues, M.R., Moreira, A.S.P., Journal of Inherited Metabolic Disease, 2024.

7. CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukemia: frequency, phenotype and association with disease progression

Rodrigues, C., Laranjeira, P., Pinho, A., Silva, I., Silva, S., Coucelo, M., Oliveira, A.C., Simões, A.T., Damásio, I., Silva, H.M., Urbano, M., Sarmento-Ribeiro, A.B., Geraldes, C., Domingues, M.R., Almeida, J., Criado, I., Orfao, A., Paiva, A., Frontiers in Oncology, 2024, 14.

8. Fatty Acid Profiling as a Tool for Fostering the Traceability of the Halophyte Plant Salicornia ramosissima and Contributing to Its Nutritional Valorization

Ricardo, F., Veríssimo, A.C., Maciel, E., Domingues, M.R., Calado, R., Plants, 2024, 13 (4).

9. Marine Animal Co-Products—How Improving Their Use as Rich Sources of Health-Promoting Lipids Can Foster Sustainability

Monteiro, J.P., Domingues, M.R., Calado, R., Marine Drugs, 2024, 22 (2)

10. Effect of physical exercise on immune, inflammatory, cardiometabolic biomarkers, and fatty acids of breast cancer survivors: results from the MAMA_MOVE Gaia After Treatment trial

Joaquim, A., Góis, A., Soares, A., Garcia, C., Amarelo, A., Antunes, P., Afreixo, V., Geraldes, V., Capela, A., Viamonte, S., Alves, A.J., Ferreira, H.B., Guerra, I., Afonso, A.I., Domingues, M.R., Helguero, L.A., Supportive Care in Cancer, 2024, 32 (3).

11. Unmasking the Metabolite Signature of Bladder Cancer: A Systematic Review

Pereira, F., Domingues, M.R., Vitorino, R., Guerra, I.M.S., Santos, L.L., Ferreira, J.A., Ferreira, R., International Journal of Molecular Sciences, 2024, 25 (6)

12. Fatty Acid Profile and Escherichia coli and Salmonella sp. Load of Wild-Caught Seaweed Fly Fucellia maritima (Haliday, 1838) (Diptera: Anthomyiidae)

Lourenço, F., Calado, R., Pinho, M., Domingues, M.R., Medina, I., Ameixa, O.M.C.C., Insects, 2024, 15 (3).

13. Short term decreases in salinity, combined with the right choice of species, can allow for a more nutritious sea lettuce lipid profile

Fort, A., Monteiro, J.P., Simon, C., Rosário Domingues, M., Sulpice, R., Food Chemistry, 2024, 437.

14. Oxidized phospholipid-protein adducts: The future targets of interest

Ferreira, H.B., Domingues, M.R., Archives of Biochemistry and Biophysics, 2024, 754.



34. Mitochondria-associated membranes (MAMs) as modulators of oxidative stress in Alzheimer disease

Fernandes, T., Domingues, M.R., Pereira, C.F., Moreira, P.I., Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects, 2023, pp. 81-96.

33. Algal lipids: structural diversity, analysis and applications

Lopes, D., Aveiro, S.S., Conde, T., Rey, F., Couto, D., Melo, T., S.P. Moreira, A., Domingues, M.R., Functional Ingredients from Algae for Foods and Nutraceuticals, Second Edition, 2023, pp. 335-396.

32. Polar Lipids of Marine Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis Mitigate the LPS-Induced Pro-Inflammatory Response in MacrophagesConde, T., Neves, B., Couto, D., Melo, T., Lopes, D., Pais, R., Batista, J., Cardoso, H., Silva, J.L., Domingues, P., Domingues, M.R., Marine Drugs, 2023, 21.

31. Lipidomic assessment of the impact of Nannochloropsis oceanica microalga lipid extract on human skin keratinocytes exposed to chronic UVB radiationŁuczaj, W., Gęgotek, A., Conde, T., Domingues, M.R., Domingues, P., Skrzydlewska, E., Scientific Reports, 2023, 13.

30. Analysis of Phosphatidylinositol Modifications by Reactive Nitrogen Species Using LC-MS: Coming to Grips with Their Nitroxidative Susceptibility

Bonciarelli, S., Neves, B., Domingues, P., Melo, T., Goracci, L., Domingues, M.R., Journal of the American Society for Mass Spectrometry, 2023, 34.

29. New method for isolating β-sitosterol from bleaching effluent of sulphite pulp mill

Evtyugin, D.D., Prates, A., Domingues, M.R., Casal, S., Evtuguin, D.V., Food and Bioproducts Processing, 2023, 140.

28. Whole Blood and Plasma-Based Lipid Profiling Reveals Distinctive Metabolic Changes in Systemic Lupus Erythematosus and Systemic Sclerosis

Ferreira, H.B., Melo, T., Guerra, I.M.S., Moreira, A.S.P., Laranjeira, P., Paiva, A., Goracci, L., Bonciarelli, S., Domingues, P., Domingues, M.R., Journal of Proteome Research, 2023, 22.

27. Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production

Evtyugin, D.D., Evtuguin, D.V., Casal, S., Domingues, M.R., Molecules, 2023, 28.

26. Restorative Effect of Microalgae Nannochloropsis oceanica Lipid Extract on Phospholipid Metabolism in Keratinocytes Exposed to UVB Radiation

Biernacki, M., Conde, T., Stasiewicz, A., Surażyński, A., Domingues, M.R., Domingues, P., Skrzydlewska, E., International Journal of Molecular Sciences, 2023, 24.

25. Optimization of Pavlova gyrans biomass production and the fatty acid profile using a two-step approach

Maciel, F., Couto, D., Geada, P., Pereira, H., Teixeira, J., Domingues, M.R., Silva, J., Vicente, A., n, 2023, 1.

24. Current trends in the traceability of geographic origin and detection of species-mislabeling in marine bivalves

Santos, A., Ricardo, F., Domingues, M.R.M., Patinha, C., Calado, R., Food Control, 2023, 152.

23. Revealing the polar lipidome, pigment profiles, and antioxidant activity of the giant unicellular green alga, Acetabularia acetabulum

Rey, F., Cartaxana, P., Cruz, S., Melo, T., Domingues, M.R, Journal of Phycology, 2023, 22.

22An overview of food lipids toward food lipidomics

Tietel, Z., Hammann, S., Meckelmann, S.W., Ziv, C., Pauling, J.K., Wölk, M., Würf, V., Alves, E., Neves, B., Domingues, M.R., Comprehensive Reviews in Food Science and Food Safety, 2023, 22.

21. Inhibiting SETD7 methyl-transferase activity impairs differentiation, lipid metabolism and lactogenesis in mammary epithelial cells

Monteiro, F.L., Góis, A., Direito, I., Melo, T., Neves, B., Alves, M.I., Batista, I., Domingues, M.D.R., Helguero, L.A., FEBS Letters, 2023, 597.

20. Optimization of a hybrid bacterial/Arabidopsis thaliana fatty acid synthase system II in Saccharomyces cerevisiae

Pozdniakova, T.A., Cruz, J.P., Silva, P.C., Azevedo, F., Parpot, P., Domingues, M.R., Carlquist, M., Johansson, B., Metabolic Engineering Communications, 2023, 17.

19. Lipidomic fingerprinting of the red seaweed Asparagopsis spp. evidencing specific profiling in gametophyte and tetrasporophyte life stages

Lopes, D., Rey, F., Melo, T., Pinho, M., Moreira, A.S.P., Pes, K., Mata, L., Domingues, M.R., Algal Research, 2024, 77.

18. Differences and Similarities in Lipid Composition, Nutritional Value, and Bioactive Potential of Four Edible Chlorella vulgaris Strains

Maurício, T., Couto, D., Lopes, D., Conde, T., Pais, R., Batista, J., Melo, T., Pinho, M., Moreira, A.S.P., Trovão, M., Barros, A., Cardoso, H., Silva, J., Domingues, P., Domingues, M.R., Foods, 2023, 12(8).

17. Study of the viability of using lipase-hydrolyzed commercial vegetable oils to produce microbially conjugated linolenic acid-enriched milk

Fontes, A.L., Pimentel, L.L., Soares, A.M.S., Domingues, M.D.R., Rodríguez-Alcalá, L.M., Gomes, A.M., Food Chemistry, 2023, 413.

16. Bioconversion of olive oil pomace by black soldier fly increases eco-efficiency in solid waste stream reduction producing tailored value-added insect meals

Ameixa, O.M.C.C., Pinho, M., Domingues, M.R., Lillebø, A.I., PLoS ONE, 2023, 18.

15. Prevention of UVB Induced Metabolic Changes in Epidermal Cells by Lipid Extract from Microalgae Nannochloropsis oceanica

Stasiewicz, A., Conde, T., Gęgotek, A., Domingues, M.R., Domingues, P., Skrzydlewska, E., International Journal of Molecular Sciences, 2023, 24(14).

14. Cross-stress lipid response of Tetraselmis striata CTP4 to temperature and salinity variation

Conde, T., Aveiro, S., Melo, T., Santos, T., Neves, B., Domingues, P., Varela, J., Pereira, H., Domingues, M.R., Algal Research, 2023, 74.

13. New method for isolating β-sitosterol from bleaching effluent of sulphite pulp mill

Evtyugin, D.D., Prates, A., Domingues, M.R., Casal, S., Evtuguin, D.V., Food and Bioproducts Processing, 2023, 140.

12. Current trends in the traceability of geographic origin and detection of species-mislabeling in marine bivalves

Santos, A., Ricardo, F., Domingues, M.R.M., Patinha, C., Calado, R., Food Control, 2023, 152.

11. Mapping the Polar Lipidome of Macroalgae using LC-MS-Based Approaches for Add-Value Applications

Lopes, D., Rey, F., Melo, T., P. Moreira, A.S., Marques, F., Abreu, M.H., Domingues, P., Domingues, M.R., European Journal of Lipid Science and Technology, 2023.

10. Water-Soluble Saccharina latissima Polysaccharides and Relation of Their Structural Characteristics with In Vitro Immunostimulatory and Hypocholesterolemic Activities

Moreira, A.S.P., Gaspar, D., Ferreira, S.S., Correia, A., Vilanova, M., Perrineau, M.-M., Kerrison, P.D., Gachon, C.M.M., Domingues, M.R., Coimbra, M.A., Coreta-Gomes, F.M., Nunes, C., Marine Drugs, 2023, 21(3)

9. Potato Chips Byproducts as Feedstocks for Developing Active Starch-Based Films with Potential for Cheese Packaging

Peixoto, A.M., Petronilho, S., Domingues, M.R., Nunes, F.M., Lopes, J., Pettersen, M.K., Grøvlen, M.S., Wetterhus, E.M., Gonçalves, I., Coimbra, M.A., Foods, 2023, 12(6).

10. A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases Fernandes, T., Domingues, M.R., Moreira, P.I., Pereira, C.F., Biology, 2023, 12(3)

9. Evaluation of Lipid Extracts from the Marine Fungi Emericellopsis cladophorae and Zalerion maritima as a Source of Anti-Inflammatory, Antioxidant and Antibacterial Compounds

Abraúl, M., Alves, A., Hilário, S., Melo, T., Conde, T., Domingues, M.R., Rey, F., Marine Drugs, 2023, 21(4).

8. Lab-on-Valve Automated and Miniaturized Assessment of Nanoparticle Concentration Based on Light-Scattering

Marques, S.S., Ramos, I.I., Silva, C., Barreiros, L., Domingues, M.R., Segundo, M.A., Analytical Chemistry, 2023, 95(10).

7. The chemodiversity of polar lipidomes of microalgae from different taxa

Couto, D., Conde, T.A., Melo, T., Neves, B., Costa, M., Silva, J., Domingues, R., Domingues, P., Algal Research, 2023, 70, 103006.

6. Study of the viability of using lipase-hydrolyzed commercial vegetable oils to produce microbially conjugated linolenic acid-enriched milk

Fontes, A.L., Pimentel, L.L., Soares, A.M.S., Domingues, M.D.R., Rodríguez-Alcalá, L.M., Gomes, A.M., Food Chemistry, 2023, 413, 135665.

5. Lipidomic Characterization and Antioxidant Activity of Macro- and Microalgae Blend

Marques, F., Lopes, D., Conde, T., Melo, T., Silva, J., Abreu, M.H., Domingues, P., Domingues, M.R., Life, 2023, 13(1), 231.

4. New solvent-free method for isolating ellagic acid from sulphite spent liquor

Evtyugin, D.D., Prates, A., Domingues, M.R., Casal, S., Evtuguin, D.V., Journal of Cleaner Production, 2023, 384, 135634.

3. Light modulates the lipidome of the photosynthetic sea slug Elysia timida

Rey, F., Cartaxana, P., Aveiro, S., Greenacre, M., Melo, T., Domingues, P., Domingues, M.R., Cruz, S., Biochimica et Biophysica Acta – Molecular and Cell Biology of Lipids, 2023, 1868(2), 159249.

2. Effect of oxidation and in vitro intestinal hydrolysis on phospholipid toxicity towards HT29 cell line serving as a model of human intestinal epithelium

 Parchem, K., Baranowska, M., Kościelak, A., Kłosowska-Chomiczewska, I., Domingues, M.R., Macierzanka, A., Bartoszek, A., Food Research International, 2023, 163, 112227

1. Lipidomics of common octopus’ (Octopus vulgaris) arm muscle using untargeted high-resolution liquid chromatography-mass spectrometry

Gaspar L., Ricardo F., Melo T., Domingues P., Domingues M.R., Calado R., Rey F., Journal of Food Composition and Analysis, 2023, 2023115, 104871


33. Lipid profile variability in children at different ages measured in dried blood spots

Ferreira, H.B., Melo, T., Rocha, H., Paiva, A., Domingues, P., Domingues, M.R., Molecular Omics, 2022

32. Mitochondrial Fatty Acid β-Oxidation Disorders: From Disease to Lipidomic Studies—A Critical Review

Guerra, I.M.S., Ferreira, H.B., Melo, T., Rocha, H., Moreira, S., Diogo, L., Domingues, M.R., Moreira, A.S.P., International Journal of Molecular Sciences, 2022, 23, 13933

31. Stearoyl CoA Desaturase-1 Silencing in Glioblastoma Cells: Phospholipid Remodeling and Cytotoxicity Enhanced upon Autophagy Inhibition

Morais, C.M., Cardoso, A.M., Araújo, A.R.D., Reis, A., Domingues, P., Domingues, M.R.M., de Lima, M.C.P., Jurado, A.S. International Journal of Molecular Sciences, 2022, 23, 13014

30. The plasma phospholipidome of the bottlenose dolphin (Tursiops truncatus) is modulated by both sex and developmental stage

Monteiro, J.P., Ferreira, H.B., Melo, T., Flanagan, C., Urbani, N., Neves, J., Domingues, P., Domingues, M.R. Molecular Omics, 2022.

29. Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line

Ferreira S.S., Domingues M.R., Barros C., Santos S.A.O., Silvestre A.J.D., Silva A.M., Nunes F.M., Food Chemistry, 2022, 16, 100468

28. Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific manner

Savva C., Helguero L.A., González-Granillo M., Melo T., Couto D., Angelin B., Domingues M.R., Li X., Kutter C., Korach-André M., Communications Biology, 2022, 5(1), 1057

27. Dried blood spots in clinical lipidomics: optimization and recent findings

Ferreira H.B., Guerra I.M.S., Melo T., Rocha H., Moreira A.S.P., Paiva A., Domingues M.R., Analytical and Bioanalytical Chemistry, 2022, 414(24), 7085

26. Inter-individual variability of early life stages of a model marine invertebrate with a bi-phasic life cycle is shaped by contrasting oceanographic conditions

Leal M.C., Rey F., Ferreira G.D., Domingues M.R., Calado R., Frontiers in Marine Science, 2022, 9, 984569

25. Nutritional stress legacy in the shrimp Palaemon varians and its implications for aquaculture production

Calado R., Freitas E., Vercesi K., Hayd L., Ricardo F., Domingues M.R., Aquaculture Reports, 2022, 25, 101195

24. Evaluation of parental and transgenerational effects of clotrimazole in Daphnia magna — A multi-parametric approach

Ferreira D., Alkimin G.D.D., Neves B., Conde T., Domingues M.R., Nunes B., Science of the Total Environment, 2022, 831, 154677

23. Chrysotila pseudoroscoffensis as a source of high-value polar lipids with antioxidant activity: A lipidomic approach

Moreira A.S.P., Gonçalves J., Conde T.A., Couto D., Melo T., Maia I.B., Pereira H., Silva J., Domingues M.R., Nunes C., Algal Research, 2022, 66, 102756

22. Understanding the nitrolipidome: From chemistry to mass spectrometry and biological significance of modified complex lipids

Neves B., Pérez-Sala D., Ferreira H.B., Guerra I.M.S., Moreira A.S.P., Domingues P., Domingues M.R., Melo T., Progress in Lipid Research, 2022, 87, 101176

21. Larval nutritional stress affects trophic compensation of juvenile caridean shrimp Palaemon varians

Calado R., Vercesi K., Freitas E., Ricardo F., Santos S.A.O., Domingues M.R., Hayd L., Aquaculture Reports, 2022, 24, 101140

20. Looking in Depth at Oxidized Cholesteryl Esters by LC-MS/MS: Reporting Specific Fragmentation Fingerprints and Isomer Discrimination

Ferreira H.B., Barros C., Melo T., Paiva A., Domingues M.R., Journal of the American Society for Mass Spectrometry, 2022, 33(5), 793

19. Effects of outdoor and indoor cultivation on the polar lipid composition and antioxidant activity of Nannochloropsis oceanica and Nannochloropsis limnetica: A lipidomics perspective

Couto D., Conde T.A., Melo T., Neves B., Costa M., Cunha P., Guerra I., Correia N., Silva J.T., Pereira H., Varela J., Silva J., Domingues R., Domingues P., Algal Research, 2022, 64, 102718

18. Lipidome in-depth characterization highlights the nutritional value and species-specific idiosyncrasies of different Ulva species

Monteiro J.P., Costa E., Melo T., Domingues P., Fort A., Domingues M.R., Sulpice R., Algal Research, 2022, 64, 102694

17. Food grade extraction of Chlorella vulgaris polar lipids: A comparative lipidomic study

Couto D., Melo T., Conde T.A., Moreira A.S.P., Ferreira P., Costa M., Silva J., Domingues R., Domingues P., Food Chemistry, 2022, 375, 131685

16. Bioprospecting Bioactive Polar Lipids from Olive (Olea europaea cv. Galega vulgar) Fruit Seeds: LC‐HR‐MS/MS Fingerprinting and Sub‐Geographic Comparison

Alves E., Rey F., Melo T., Barros M.P., Domingues P., Domingues R., Foods, 2022, 11(7), 951

15. Maternal high-fat diet programs white and brown adipose tissue lipidome and transcriptome in offspring in a sex- and tissue-dependent manner in mice

Savva C., Helguero L.A., González-Granillo M., Melo T., Couto D., Buyandelger B., Gustafsson S., Liu J., Domingues M.R., Li X., Korach-André M., International Journal of Obesity, 2022, 46(4), 831

14. Applications of lipidomics in marine organisms: progress, challenges and future perspectives

Rey F., Melo T., Lopes D., Couto D., Marques F., Domingues M.R., Molecular Omics, 2022, 18(5), 357

13. Bioconversion and performance of Black Soldier Fly (Hermetia illucens) in the recovery of nutrients from expired fish feeds

Rodrigues D.P., Calado R., Pinho M., Rosário Domingues M., Antonio Vázquez J., Ameixa O.M.C.C., Waste Management, 2022, 141, 183

12. Comprehensive Metabolomics and Lipidomics Profiling of Prostate Cancer Tissue Reveals Metabolic Dysregulations Associated with Disease Development

Lima A.R., Carvalho M., Aveiro S.S., Melo T., Domingues M.R., Macedo-Silva C., Coimbra N., Jerónimo C., Henrique R., Bastos M.d.L., Guedes de Pinho P., Pinto J., Journal of Proteome Research, 2022, 21(3), 727

11. Human Bone Marrow Mesenchymal Stromal/Stem Cells Regulate the Proinflammatory Response of Monocytes and Myeloid Dendritic Cells from Patients with Rheumatoid Arthritis

Laranjeira P., Pedrosa M., Duarte C., Pedreiro S., Antunes B., Ribeiro T., Dos Santos F., Martinho A., Fardilha M., Domingues M.R., Abecasis M., da Silva J.A.P., Paiva A., Pharmaceutics, 2022, 14(2), 404

10. Multi-Omic Profiling of Macrophages Treated with Phospholipids Containing Omega-3 and Omega-6 Fatty Acids Reveals Complex Immunomodulatory Adaptations at Protein, Lipid and Metabolic Levels

Maurício T., Aveiro S., Guedes S., Lopes D., Melo T., Neves B.M., Domingues R., Domingues P., International Journal of Molecular Sciences, 2022, 23(4), 2139

9. Adaptation of Lipid Profiling in Depression Disease and Treatment: A Critical Review

Pinto B., Conde T., Domingues I., Domingues M.R., International Journal of Molecular Sciences, 2022, 23(4), 2032

8. Algal Lipids as Modulators of Skin Disease: A Critical Review

Conde T., Lopes D., Łuczaj W., Neves B., Pinto B., Maurício T., Domingues P., Skrzydlewska E., Rosário Domingues M., Metabolites, 2022, 12(2), 96

7. Bioprospecting antibiotic properties in photodynamic therapy of lipids from Codium tomemtosum and Chlorella vulgaris

Bartolomeu M., Vieira C., Dias M., Conde T., Couto D., Lopes D., Neves B., Melo T., Rey F., Alves E., Silva J., Abreu H., Almeida A., Domingues M.R., Biochimie, 2022

6. Production of a food grade extract of Chlorococcum amblystomatis rich in omega-3 lipids using ethanol assisted with ultrasound and deep characterization by lipidomics

Conde T., Couto D., Melo T., Moreira A.S.P., Ferreira P., Costa M., Silva J., Neves B., Domingues P., Domingues M.R., Journal of Applied Phycology, 2022

5. Hemp Seeds, Flaxseed, and Açaí Berries: Health Benefits and Nutritional Importance with Emphasis on the Lipid Content

Magalhães P., Domingues R.M., Alves E., Current Nutrition and Food Science, 2022, 18(1), 4

4. Lipids of Marine Algae—Biomolecules with High Nutritional Value and Important Bioactive Properties

Rosário Domingues M., Calado R., Biomolecules, 2022, 12(1), 134

3. Potential anti-obesity, anti-steatosis, and anti-inflammatory properties of extracts from the microalgae Chlorella vulgaris and Chlorococcum amblystomatis under different growth conditions

Regueiras A., Huguet Á., Conde T., Couto D., Domingues P., Domingues M.R., Costa A.M., da Silva J.L., Vasconcelos V., Urbatzka R., Marine Drugs, 2022, 20(1), 9

2. Fatty acid ratio analysis identifies changes in competent meroplanktonic larvae sampled over different supply events

Rey F., Greenacre M., Silva Neto G.M., Bueno-Pardo J., Domingues M.R., Calado R., Marine Environmental Research, 2022, 173, 105517

1. Exhaustive reanalysis of barcode sequences from public repositories highlights ongoing misidentifications and impacts taxa diversity and distribution

Fort A., McHale M., Cascella K., Potin P., Perrineau M.-M., Kerrison P.D., da Costa E., Calado R., Domingues M.D.R., Costa Azevedo I., Sousa-Pinto I., Gachon C., van der Werf A., de Visser W., Beniers J.E., Jansen H., Guiry M.D., Sulpice R., Molecular Ecology Resources, 2022, 22(1), 86



31. Halophyte plants cultured in aquaponics hold the same potential for valorization as wild conspecifics from donor sites

Marques, B., Maciel, E., Domingues, M.R., Calado, R., Lillebø, A.I., Applied Sciences (Switzerland), 2021, 11(24), 11586

30. Bioactivities of lipid extracts and complex lipids from seaweeds: Current knowledge and future prospects

Lopes, D., Rey, F., Leal, M.C., …Calado, R., Domingues, M.R., Marine Drugs, 2021, 19(12), 686

29. Seaweed blends as a valuable source of polyunsaturated and healthy fats for nutritional and food applications

Marques, F., Lopes, D., da Costa, E., …Abreu, M.H., Domingues, M.R., Marine Drugs, 2021, 19(12), 684

28. Hydrophobic starch-based films using potato washing slurries and spent frying oil

Petronilho, S., Oliveira, A., Domingues, M.R., …Coimbra, M.A., Gonçalves, I., Foods, 2021, 10(12), 2897

27. Unravelling the fatty acid profiles of different polychaete species cultured under integrated multi-trophic aquaculture (IMTA)

Jerónimo, D., Lillebø, A.I., Maciel, E., …Cremades, J., Calado, R., Scientific Reports, 2021, 11(1), 10812

26. Polar lipidomic profile shows Chlorococcum amblystomatis as a promising source of value-added lipids

Conde, T.A., Couto, D., Melo, T., …Domingues, M.R., Domingues, P., Scientific Reports, 2021, 11(1), 4355

25. Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in life

Savva, C., Helguero, L.A., González-Granillo, M., …Kutter, C., Korach-André, M., Communications Biology, 2021, 4(1), 14

24. Salinity shapes the stress responses and energy reserves of marine polychaetes exposed to warming: From molecular to functional phenotypes

Madeira, D., Fernandes, J.F., Jerónimo, D., …Diniz, M.S., Calado, R., Science of the Total Environment, 2021, 795, 148634

23. Improving agar properties of farmed Gracilaria gracilis by using filtered sunlight

Silva-Brito, F., Pereira, S.G., Rocha, C.M.R., …Abreu, H., Magnoni, L., Journal of Applied Phycology, 2021, 33(5), 3397–3411

22. Modulation of fatty acid profiles by global and local ocean change drivers in the ragworm Hediste diversicolor: implications for aquaculture production

Fernandes, J.F., Ricardo, F., Jerónimo, D., …Calado, R., Madeira, D., Aquaculture, 2021, 542, 736871

21. Microalgal lipid extracts have potential to modulate the inflammatory response: A critical review

Conde, T.A., Zabetakis, I., Tsoupras, A., …Domingues, P., Domingues, M.R., International Journal of Molecular Sciences, 2021, 22(18), 9825

20. The plasma phospholipidome of Tursiops truncatus: From physiological insight to the design of prospective tools for managed cetacean monitorization

Monteiro, J.P., Maciel, E., Melo, T., …Neves, J., Domingues, M.R., Lipids, 2021, 56(5), 461–473

19. Changes in phospholipid/ceramide profiles and eicosanoid levels in the plasma of rats irradiated with UV rays and treated topically with cannabidiol

Łuczaj, W., Jastrząb, A., Domingues, M.D.R., Domingues, P., Skrzydlewska, E., International Journal of Molecular Sciences, 2021, 22(16), 8700

18. Screening for health-promoting fatty acids in ascidians and seaweeds grown under the influence of fish farming activities

Marques, L., Domingues, M.R., da Costa, E., …Lillebø, A.I., Calado, R., Marine Drugs, 2021, 19(8), 469

17. Polar lipids composition, antioxidant and anti-inflammatory activities of the atlantic red seaweed Grateloupia turuturu

da Costa, E., Melo, T., Reis, M., …Abreu, M.H., Domingues, M.R., Marine Drugs, 2021, 19(8), 414

16. Evaluation of the Potential of Marine Algae Extracts as a Source of Functional Ingredients Using Zebrafish as Animal Model for Aquaculture

Monteiro, M., Lavrador, A.S., Santos, R., …Enes, P., Díaz-Rosales, P., Marine Biotechnology, 2021, 23(4), 529–545

15. Microalgae as sustainable bio-factories of healthy lipids: Evaluating fatty acid content and antioxidant activity

Conde, T.A., Neves, B.F., Couto, D., …Domingues, P., Domingues, M.R., Marine Drugs, 2021, 19(7), 357

14. Optimizing the Timeframe to Produce Polychaetes (Hediste diversicolor) Enriched With Essential Fatty Acids Under Different Combinations of Temperature and Salinity

Jerónimo, D., Lillebø, A.I., Rey, F., …Domingues, M.R.M., Calado, R., Frontiers in Marine Science, 2021, 8, 671545

13. Plasma Phospholipidomic Profile Differs between Children with Phenylketonuria and Healthy Children

Guerra, I.M.S., Diogo, L., Pinho, M., …Domingues, M.R., Moreira, A.S.P., Journal of Proteome Research, 2021, 20(5), 2651–2661

12. Polar lipids of commercial Ulva spp. of different origins: Profiling and relevance for seaweed valorization

Moreira, A.S.P., da Costa, E., Melo, T., …Domingues, P., Domingues, M.R., Foods, 2021, 10(5), 914

11. Insights of species-specific polar lipidome signatures of seaweeds fostering their valorization in the blue bioeconomy

Lopes, D., Melo, T., Rey, F., …Calado, R., Rosário Domingues, M., Algal Research, 2021, 55, 102242

10. Calcium homeostasis and stable fatty acid composition underpin heatwave tolerance of the keystone polychaete Hediste diversicolor

Madeira, D., Fernandes, J.F., Jerónimo, D., …Domingues, M.R., Calado, R., Environmental Research, 2021, 195, 110885

9. Effect of harvesting month and proximity to fish farm sea cages on the lipid profile of cultivated Saccharina latissima

Monteiro, J.P., Melo, T., Skjermo, J., …Calado, R., Domingues, M.R., Algal Research, 2021, 54, 102201

8. Characterization of Non-volatile Oxidation Products Formed from Triolein in a Model Study at Frying Temperature

Petronilho, S., Neves, B., Melo, T., …Coimbra, M.A., Domingues, M.R., Journal of Agricultural and Food Chemistry, 2021, 69(11), 3466–3478

7. Chemoplasticity of the polar lipid profile of the microalgae Chlorella vulgaris grown under heterotrophic and autotrophic conditions

Couto, D., Melo, T., Conde, T.A., …Domingues, M.R.M., Domingues, P., Algal Research, 2021, 53, 102128

6. Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays

Silva, L.M., Correia, V.G., Moreira, A.S.P., …Coimbra, M.A., Palma, A.S., Carbohydrate Polymers, 2021, 253, 117350

5. Serum phospholipidomics reveals altered lipid profile and promising biomarkers in multiple sclerosis

Ferreira, H.B., Melo, T., Monteiro, A., …Domingues, P., Domingues, M.R., Archives of Biochemistry and Biophysics, 2021, 697, 108672

4. Exhaustive reanalysis of barcode sequences from public repositories highlights ongoing misidentifications and impacts taxa diversity and distribution

Fort, A., McHale, M., Cascella, K., …Guiry, M.D., Sulpice, R., Molecular Ecology Resources, 2021

3. Characterization of the cardiac phospholipidome of small cetaceans provides adaptational insight and a foundation for indirect population health screening

Monteiro, J.P., Maciel, E., Maia, R., …Eira, C., Domingues, M.R., Marine Mammal Science, 2021

2. Insights in the role of lipids, oxidative stress and inflammation in rheumatoid arthritis unveiled by new trends in lipidomic investigations

Ferreira, H.B., Melo, T., Paiva, A., Domingues, M.D.R., Antioxidants, 2021, 10(1), 1–21, 45

1. Fruit seeds and their oils as promising sources of value-added lipids from agro-industrial byproducts: oil content, lipid composition, lipid analysis, biological activity and potential biotechnological applications

Alves, E., Simoes, A., Domingues, M.R., Critical Reviews in Food Science and Nutrition, 2021, 61(8), pp. 1305–1339




27. Changes in lipid profile of keratinocytes from rat skin exposed to chronic uva or uvb radiation and topical application of cannabidiol

Łuczaj, W., Domingues, M.D.R., Domingues, P., Skrzydlewska, E., Antioxidants, 2020, 9(12), 1–15, 1178

26. Revealing the illegal harvesting of Manila clams (Ruditapes philippinarum) using fatty acid profiles of the adductor muscle

Mamede, R., Ricardo, F., Santos, A., Domingues, M.R.M., Calado, R., Food Control, 2020, 118, 107368

25. Nutrient availability affects the polar lipidome of Halimione portulacoides leaves cultured in hydroponics

Custódio, M., Maciel, E., Domingues, M.R., Lillebø, A.I., Calado, R., Scientific Reports, 2020, 10(1), 6583

24. Screening for polar lipids, antioxidant, and anti-inflammatory activities of Gloeothece sp. lipid extracts pursuing new phytochemicals from cyanobacteria

da Costa, E., Amaro, H.M., Melo, T., Guedes, A.C., Domingues, M.R., Journal of Applied Phycology, 2020, 32(5), 3015–3030

23. Cannabidiol-mediated changes to the phospholipid profile of uvb-irradiated keratinocytes from psoriatic patients

Łuczaj, W., Dobrzyńska, I., Wroński, A., Domingues, P., Skrzydlewska, E., International Journal of Molecular Sciences, 2020, 21(18), 1–17, 6592

22. Valuing Bioactive Lipids from Green, Red and Brown Macroalgae from Aquaculture, to Foster Functionality and Biotechnological Applications

Lopes, D., Melo, T., Rey, F., Calado, R., Domingues, M.R., Molecules, 2020, 25(17), 3883

21. An overview of lipidomic analysis in different human matrices of multiple sclerosis

Ferreira, H.B., Neves, B., Guerra, I.M., Paiva, A., Domingues, M.R., Multiple Sclerosis and Related Disorders, 2020, 44, 102189

20. Differential modulation of the phospholipidome of proinflammatory human macrophages by the flavonoids quercetin, naringin and naringenin

Conde, T.A., Mendes, L., Gaspar, V.M., Domingues, M.R., Duarte, I.F., Molecules, 2020, 25(15), 3460

19. Antimicrobial lipids from plants and marine organisms: An overview of the current state‐of‐the‐ art and future prospects

Alves, E., Dias, M., Lopes, D., Domingues, M.D.R., Rey, F., Antibiotics, 2020, 9(8), 1–88, 441

18. Seasonal plasticity of the polar lipidome of Ulva rigida cultivated in a sustainable integrated multi-trophic aquaculture

Moreira, A.S.P., da Costa, E., Melo, T., Calado, R., Domingues, M.R., Algal Research, 2020, 49, 101958

17. Halophyte plants from sustainable marine aquaponics are a valuable source of omega-3 polar lipids

Maciel, E., Domingues, P., Domingues, M.R.M., Calado, R., Lillebø, A., Food Chemistry, 2020, 320, 126560

16. Lipids and phenylketonuria: Current evidences pointed the need for lipidomics studies

Guerra, I.M.S., Ferreira, H.B., Neves, B., Domingues, M.R., Moreira, A.S.P., Archives of Biochemistry and Biophysics, 2020, 688, 108431

15. Coping with starvation: Contrasting lipidomic dynamics in the cells of two sacoglossan sea slugs incorporating stolen plastids from the same macroalga

Rey, F., Melo, T., Cartaxana, P., Cruz, S., Domingues, M.R.M., Integrative and Comparative Biology, 2020, 60(1), 43–56

14. Unraveling the lipidome and antioxidant activity of native Bifurcaria bifurcata and invasive sargassum muticum seaweeds: A lipid perspective on how systemic intrusion may present an opportunity

Santos, F., Monteiro, J.P., Duarte, D., da Costa, E., Domingues, M.R., Antioxidants, 2020, 9(7), 1–20, 642

13. Advancing target identification of nitrated phospholipids in biological systems by HCD specific fragmentation fingerprinting in orbitrap platforms

Neves, B., Duarte, S., Domingues, P., Do Rosário Domingues, M., Melo, T., Molecules, 2020, 25(9), molecules25092120

12. Sphingomyelins prevent propagation of lipid peroxidation—LC-MS/MS evaluation of inhibition mechanisms

Coliva, G., Lange, M., Colombo, S., Rosario Domingues, M., Fedorova, M., Molecules, 2020, 25(8), 1925

11. Insights on ultrafiltration-based separation for the purification and quantification of methotrexate in nanocarriers

Marques, S.S., Ramos, I.I., Fernandes, S.R., Domingues, M.R.M., Segundo, M.A., Molecules, 2020, 25(8), 25081879

10. Lipidomic analysis of human primary hepatocytes following LXR activation with GW3965 identifies AGXT2L1 as a main target associated to changes in phosphatidylethanolamine

Santinha, D., Klopot, A., Marques, I., Mode, A., Helguero, L.A., Journal of Steroid Biochemistry and Molecular Biology, 2020, 198, 105558

9. Elevated soluble TNFα levels and upregulated TNFα mRNA expression in purified peripheral blood monocyte subsets associated with high-grade hepatocellular carcinoma

Martín-Sierra, C., Martins, R., Coucelo, M., Paiva, A., Laranjeira, P., Journal of Inflammation (United Kingdom), 2020, 17(1), 14

8. Site-specific lipidomic signatures of sea lettuce (Ulva spp., chlorophyta) hold the potential to trace their geographic origin

da Costa, E., Ricardo, F., Melo, T., Domingues, M.R., Calado, R., Biomolecules, 2020, 10(3), 489

7. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

Kapralov, A.A., Yang, Q., Dar, H.H., Bayır, H., Kagan, V.E., Nature Chemical Biology, 2020, 16(3), 278–290

6. Tumor Resection Induces Alterations on Serum Phospholipidome of Liver Cancer Patients

Martín-Sierra, C., Colombo, S., Martins, R., Domingues, M.R., Paiva, A., Lipids, 2020, 55(2), 185–191

5. Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells

Magalhães-Novais, S., Bermejo-Millo, J.C., Loureiro, R., Oliveira, P.J., Vega-Naredo, I., Autophagy, 2020, 16(2), 313–333

4. Lipidomic analysis reveals specific differences between fibroblast and keratinocyte ceramide profile of patients with psoriasis vulgaris

Łuczaj, W., Wroński, A., Domingues, P., Rosário Domingues, M., Skrzydlewska, E., Molecules, 2020, 25(3), 630

3. Domesticated populations of Codium tomentosum display lipid extracts with lower seasonal shifts than conspecifics from the wild-relevance for biotechnological applications of this green seaweed

Rey, F., Cartaxana, P., Melo, T., Cruz, S., Rosário Domingues, M., Marine Drugs, 2020, 18(4), 18040188

2. The unique lipidomic signatures of Saccharina latissima can be used to pinpoint their geographic origin

Monteiro, J.P., Rey, F., Melo, T., Calado, R., Domingues, M.R., Biomolecules, 2020, 10(1), 107

1. Immunomodulatory effect of human bone marrow-derived mesenchymal stromal/stem cells on peripheral blood T cells from rheumatoid arthritis patients

Pedrosa, M., Gomes, J., Laranjeira, P., P. da Silva, J.A., Paiva, A., Journal of Tissue Engineering and Regenerative Medicine, 2020, 14(1), 16–28